What is Leaky Gut?
The term "Leaky Gut" describes an increase in intestinal permeability. This means that the strong intestinal barrier has become compromised. The lining is made of tight epithelial cells with junctions in between. When these junctions become weak, they allow large molecules to pass into the bloodstream. This causes a variety of undesirable reactions in the body.
What disrupts the Intestinal Lining?
The things listed below contribute to an increase in permeability:
Alcohol
Frequent NSAID use
A diet high in processed food
Stress
Radiation and chemotherapy
Infectious organisms
High sugar diets
Prolonged or frequent antibiotic use
Genetically modified organisms (GMO)
Signs and Symptoms
Symptoms vary per individual, but can include any of the following:
Food intolerances
Bloating/gas
Changes in bowel patterns
Brain fog
Fatigue
Joint and muscle pain
Other than undesirable symptoms, a leaky gut can be associated with various medical conditions such as allergies and asthma, autoimmune conditions, irritable bowel syndrome, depression, anxiety, Alzheimer's, and metabolic syndrome.
How does this affect the rest of our body?
Having a leaky gut causes a generalized inflammatory response within the body. Some other impacts include those on immunity and mental health.
The microbiome (community of organisms within our gut) produces approximately 70% of our immune cells. An imbalance in the bacteria along with a compromised lining will result in a down-regulated immune system.
There is direct communication between the brain and gut via the vagal nerve. This area of study, known as the gut-brain axis, has helped us to understand how the gut affects cognitive function. Many neurotransmitters, including 90% of our serotonin, are produced in the gut. When we experience dysbiosis, an imbalance in the ratios of flora, this can also impact our mental health.
Nutritional Intervention
These are a few dietary measures to facilitate a healthy gut lining.
Eating plenty of fermentable dietary fiber helps provide fuel for microbes
Omega-3's help mediate inflammation
Glutamine is an amino acid that helps reduce inflammation
Collagen helps support the lining by healing epithelial tissue
Probiotic-rich foods such as kefir
Treatment
Avoid known irritants to the gastric lining when able. Modifying diet and removing pro-inflammatory foods may be necessary. Supplements and strain-specific probiotic therapy may be beneficial and are best recommended by a practitioner who understands this condition. Managing stress and routine exercise can both facilitate a healthier microbiome.
Summary
The concept of "Leaky Gut" may be new to some, but thanks to plentiful research there is a much better understanding of this topic. Since symptoms vary among individuals, getting an accurate diagnosis and treatment plan may take time. Working with a practitioner who has knowledge of this topic is helpful. Once identified and proper treatment initiated, healing can be achieved.
Sources
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