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Writer's pictureJennifer Oruwari

Diabetes Demystified: Its Impact from Head to Toe



"Did you know that over 400 million people worldwide live with diabetes, many of whom are unaware of its full impact on their bodies?" 


Most people associate diabetes with high blood sugar levels and the need for insulin. While these are important aspects of the disease, they do not provide the full picture. This common view makes diabetes seem simple and overlooks how complex it is.


In this article, we will address the misconception people have about diabetes and provide a more accurate understanding of diabetes, its types and how it can be managed and the demographics of those most affected by diabetes.

First, what exactly is diabetes and why is it a serious concern?

Diabetes is a chronic condition that disrupts how your body processes sugar (glucose). If unmanaged, it can harm multiple organs and systems, leading to severe complications.

And yet, many people are unaware of how far-reaching its effects can be. Though managing blood sugar is critical, diabetes is far more than just a glucose problem.

Types of Diabetes: What Sets Them Apart?

Not all diabetes is the same! Let’s break down the main types to help you understand how they differ:

Type 1 Diabetes:

  • What it is: An autoimmune condition where the body’s immune system attacks insulin-producing cells in the pancreas.

  • Who it affects: It is often diagnosed in children or young adults, but it can occur at any age.

Key feature: Insulin dependence—people with Type 1 must take insulin daily to survive.


Type 2 Diabetes:

  • What it is: A condition where the body becomes resistant to insulin or doesn’t produce enough for the body.

  • Who it affects: It is common in adults over 45, but it is becoming increasingly prevalent among younger people due to lifestyle factors.

  • Key feature: It is often managed through diet, exercise, medication, and sometimes insulin.


Gestational Diabetes:

  • What it is: A temporary form of diabetes that develops during pregnancy.

  • Who it affects: Pregnant women, typically in the second or third trimester.

  • Key feature: Usually resolves after childbirth but increases the risk of Type 2 diabetes later in life.

Symptoms of Diabetes

Recognizing the symptoms of diabetes is crucial in managing these different types of the disease effectively and for early detection. While symptoms may vary between Type 1 and Type 2 diabetes, here are some common signs to watch for:


  • Increased Thirst and Frequent Urination: High blood sugar levels force your kidneys to work harder, leading to excessive urination (polyuria) and dehydration, which causes thirst (polydipsia).

  • Extreme Hunger (Polyphagia): Despite eating, people with diabetes may feel unusually hungry because the body isn’t effectively using glucose for energy.

  • Unexplained Weight Loss: The body starts breaking down fat and muscle for energy when it can’t access glucose, leading to rapid weight loss.

  • Fatigue: Insufficient glucose in cells due to insulin resistance or deficiency can result in constant tiredness and lack of energy.

  • Tingling or Numbness in Hands and Feet: This symptom known as peripheral neuropathy, this symptom results from nerve damage caused by prolonged high blood sugar levels.

  • Darkened Skin Patches: A condition called acanthosis nigricans causes dark, velvety skin patches, often in areas like the neck or armpits, and is a sign of insulin resistance.


Type 1 Diabetes-Specific Symptoms:

  • Sudden onset of symptoms

  • Nausea or vomiting

  • Abdominal pain

Type 2 Diabetes-Specific Symptoms:

  • Symptoms often develop gradually

  • Symptoms may go unnoticed for years until complications arise

How diabetes affects your entire body

Let’s take a closer look, from head to toe at how diabetes affects your entire body and why detecting it early and managing it well can make all the difference.

  • Diabetes and its effects on Brain Function and Mental Health: Diabetes doesn’t just stop at physical health; it can significantly affect mental and cognitive health as well. Surprising right? People with diabetes are at an increased risk of developing cognitive decline and conditions like Alzheimer’s disease, often referred to as "Type 3 diabetes" due to its potential link with insulin resistance in the brain. Additionally, fluctuating blood sugar levels can trigger mood swings, anxiety, and depression, making mental health care a crucial part of diabetes management.

  • Diabetes and its effects on the Eyes and Vision: Diabetes is one of the leading causes of vision problems, including diabetic retinopathy, which occurs when high blood sugar damages the blood vessels in the retina. Over time, this can lead to blurry vision, cataracts, glaucoma, or even blindness if not treated. Regular eye exams and blood sugar control are key to protecting your vision.

  • Diabetes and its effect on Cardiovascular Health: The heart and blood vessels often bear the brunt of diabetes. High blood sugar levels can damage arteries, leading to atherosclerosis (a condition where the blood vessels harden and narrow, reducing blood flow). This increases the risk of heart attacks, strokes, and high blood pressure. In fact, people with diabetes are twice as likely to develop cardiovascular disease as those without the condition. Keeping cholesterol and blood pressure in check alongside glucose levels can significantly reduce these risks.

  • Diabetes and its effect on Kidney Function: The kidneys filter waste from the blood, but high glucose levels can damage the tiny blood vessels in these organs. This condition, known as diabetic nephropathy, can lead to kidney failure over time. Symptoms often go unnoticed until significant damage has occurred, so regular screenings for kidney function are crucial for people with diabetes.

  • Immune System: Diabetes weakens the immune system, making it harder for the body to fight off infections. High blood sugar can impair white blood cells, which are essential for immune defense. This is why people with diabetes are more prone to infections, including urinary tract infections, pneumonia, and slow-healing wounds.

  • Feet and Circulation: Diabetic foot problems are a significant concern. Peripheral neuropathy and poor circulation can result in ulcers, sores, and infections that don’t heal properly. Without prompt care, these issues can escalate to serious complications like gangrene. Routine foot care and proper footwear are essential to prevent these outcomes.


What Can You Do?

Now that we have a clear understanding of how diabetes impacts the entire body, causing dysfunction in organs and tissues, let's explore effective ways to prevent it.

The good news is that many of these complications are preventable with proper management and lifestyle changes. Here are a few tips:


  • Monitor Blood Sugar: Ensure to keep your glucose levels within the target range recommended by your healthcare provider.

  • Stay Active: Regular exercise improves circulation, heart health, and insulin sensitivity.

  • Eat a Balanced Diet: Focus on whole foods, low-glycemic carbohydrates, and plenty of fiber.

  • Don’t Skip Check-Ups: Regular screenings for eyes, kidneys, heart, and feet can catch complications early.

  • Manage Stress: Mental health care is equally important. Stress can worsen blood sugar levels and overall well-being.


Note that while lifestyle changes are effective, they may not always be sufficient for everyone, especially for those with genetic predispositions.

What Happens When Prevention Measures Fail, and High Sugar Levels Persist?

When efforts to manage or prevent diabetes are unsuccessful, and high blood sugar levels persist, it can lead to worsening of the complications discussed earlier. Here’s what could happen:


  • Accelerated Organ Damage: Persistently high blood sugar continues to damage organs and tissues. For instance, prolonged exposure can exacerbate kidney damage, potentially leading to end-stage renal disease, requiring dialysis or transplantation.

  • Chronic Inflammation: High sugar levels create an inflammatory environment in the body, contributing to more significant cardiovascular risks, joint problems, and immune dysfunction.

  • Increased Risk of Infections: Persistent hyperglycemia further weakens the immune system, making infections more frequent and severe. Wounds may fail to heal, increasing the risk of amputations.

  • Severe Neuropathy: If blood sugar remains unmanaged, nerve damage can worsen, leading to debilitating pain or even complete loss of sensation, increasing the risk of life-altering injuries.

Demographics of Those Most Affected by Diabetes


Age

  • Type 1 Diabetes: Most commonly diagnosed in children, adolescents, or young adults. It accounts for about 5-10% of all diabetes cases worldwide.

  • Type 2 Diabetes: More prevalent in adults over 45, but rising childhood obesity rates have caused a significant increase in cases among younger populations. Studies show that 1 in 5 adolescents in the U.S. has prediabetes, putting them at risk of developing Type 2 diabetes.


    Ethnicity

Certain ethnic groups face a disproportionately higher risk of developing Type 2 diabetes:

  • African Americans: Nearly 12.1% of African American adults in the U.S. are diagnosed with diabetes.

  • Hispanic/Latinos: The prevalence is 11.8%, with the highest rates seen among Puerto Ricans and Mexican Americans.

  • Native Americans: The highest rates of diabetes occur among Native Americans, with a prevalence of up to 14.5% in some tribes, such as the Pima Indians.

  • Asian Americans and Pacific Islanders: While overall prevalence is 9.5%, South Asian populations show higher rates of insulin resistance even at lower body weights.


    Gender

  • Diabetes affects both men and women; however, men are at a higher risk of developing Type 2 diabetes at a lower body mass index (BMI) than women. Globally, the prevalence of diabetes among men is 10.4% compared to 9.8% for women, according to the International Diabetes Federation.


    Lifestyle

  • Obesity: Over 90% of individuals with Type 2 diabetes are either overweight or obese, highlighting the strong link between excess weight and diabetes.

  • Physical Inactivity: A sedentary lifestyle is a significant contributor, with studies showing that individuals who are physically inactive have a 30-40% higher risk of developing Type 2 diabetes.

  • Smoking: Smokers are 30-40% more likely to develop diabetes than non-smokers.

  • Stress: Chronic stress can increase blood sugar levels and insulin resistance, compounding the risk.

Call to action

Seek Medical Guidance

Work closely with your healthcare provider to adjust your treatment plan. Medications, insulin therapy, lifestyle changes and options like continuous glucose monitors (CGMs) can help.

"Take charge of your health today—whether it’s scheduling a blood sugar test, walking for 30 minutes daily, or simply eating more balanced meals. Small steps can make a big difference!"


Conclusion

Diabetes is a condition that demands a whole-body approach to care. By understanding its far-reaching impacts, we can take proactive steps to minimize complications and improve quality of life.


If you have diabetes or are helping someone who does, learning and regular doctor visits are very important. Diabetes may be a lifelong condition, but with the right care, knowledge, and support, you can live a fulfilling and healthy life. Start by taking one step today!




References

Oruwari, J. (2024). From head to toe: How diabetes affects your entire body. Medium. https://medium.com/@jenniferoruwari2005/from-head-to-toe-how-diabetes-affects-your-entire-body-0f389cd55a7e

American Diabetes Association. (2024). Statistics about diabetes. Retrieved from https://www.diabetes.org/resources/statistics/statistics-about-diabetes

World Health Organization. (n.d.). Diabetes. World Health Organization. Retrieved from https://www.who.int/health-topics/diabetes

MedlinePlus. (n.d.). Diabetes. U.S. National Library of Medicine. Retrieved from https://medlineplus.gov/ency/article/000305.htm

FirstPointMD. (n.d.). Diabetes care in Floral Park, NY. FirstPointMD. https://firstpointmd.com/diabetes-management

Centers for Disease Control and Prevention (CDC). (2022). Diabetes overview. Retrieved from https://www.cdc.gov/diabetes/basics/diabetes.html

UF Health. (2017). Type 1 diabetes patients retain some ability to produce insulin, UF Health researchers find. UF Health. https://ufhealth.org/news/2017/type-1-diabetes-patients-retain-some-ability-produce-insulin-uf-health-researchers-find

Mayo Clinic. (2023). Diabetes: Symptoms and causes. Retrieved from https://www.mayoclinic.org/diseases-conditions/diabetes/symptoms-causes/syc-20320623

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). (2021). Diabetes complications. Retrieved from https://www.niddk.nih.gov/health-information/diabetes/overview/complications

American Diabetes Association. (2020). Types of insulin and how they differ. Retrieved from https://www.diabetes.org/learn-about-diabetes/treatment-and-care/insulin



Assessed and Endorsed by the MedReport Medical Review Board

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